SMBE 2013 session on microbial genome evolution

SMBE 2013 meeting session I chaired on microbial genome evolution

Storified by Jonathan Eisen · Thu, Jul 18 2013 13:53:59

At #SMBE13 Florent Lassalle: selection on codon usage vs. GC - supported model that GC biased gene conversion interfered w/ selection

— Jonathan Eisen · Mon, Jul 08 2013 09:58:29

At #SMBE13 Florent Lassalle: recombination species (of the 21 species of bacteria/archaea) are always richer in GC than non recombining ones

— Jonathan Eisen · Mon, Jul 08 2013 09:55:26

At #SMBE13 Florent Lassalle: took 21 sets of bacterial/archaeal "species" w/ many genomes in each set; looked at recombination w/in each

— Jonathan Eisen · Mon, Jul 08 2013 09:54:01

At #SMBE13 Florent Lassalle: two main predictions of GC biased gene conversion: recombination correlated w/ GC; GC interferes w/ selection

— Jonathan Eisen · Mon, Jul 08 2013 09:53:11

At #SMBE13 Florent Lassalle: much evidence for GC biased gene conversion in eukaryotes - so why not bacteria?

— Jonathan Eisen · Mon, Jul 08 2013 09:52:33

At #SMBE13 Florent Lassalle: wondered if biased gene conversion could explain some of the patterns of evolution in microbial genomes

— Jonathan Eisen · Mon, Jul 08 2013 09:51:44

At #SMBE13 Florent Lassalle: references Hersberg and Petrov PLOS Genetics paper http://www.plosgenetics.org/article/info%3Adoi/10.1371/journal.pgen.1001115 cc: @PetrovADmitri

— Jonathan Eisen · Mon, Jul 08 2013 09:50:38

Last up in the #SMBE13 microbial genome evolution session -Florent Lassalle on biased gene conversion shaping the bacterial genome landscape

— Jonathan Eisen · Mon, Jul 08 2013 09:49:38

At #SMBE13 @McCutcheonLab - genome of Tremblaya types that do not have Moranella inside of them -are less reduced than those w/ Moranella

— Jonathan Eisen · Mon, Jul 08 2013 09:43:24

At #SMBE13 @McCutcheonLab - compared symbioses across mealybugs - not all have Moranella in Tremblaya structure

— Jonathan Eisen · Mon, Jul 08 2013 09:42:08

Mealy bug symbiont within a symbiont amino acid pathway spans 3 different genomes #smbe13 see @carlzimmer post http://www.nytimes.com/2013/07/04/science/how-simple-can-life-get-its-complicated.html?_r=0

— Graham Coop · Mon, Jul 08 2013 09:40:42

At #SMBE13 @McCutcheonLab - wondered if Tremblaya transferred any genes to its host genome as in organelles

— Jonathan Eisen · Mon, Jul 08 2013 09:40:24

At #SMBE13 @McCutcheonLab - asking how/why does Tremblaya have such a degenerate genome? (only 120 genes or so)

— Jonathan Eisen · Mon, Jul 08 2013 09:39:43

At #SMBE13 @McCutcheonLab: Tremblaya is the smallest known genome "but that may fall any day"

— Jonathan Eisen · Mon, Jul 08 2013 09:38:41

At #SMBE13 @McCutcheonLab - for mealybug the synthesis of essential amino acids comes from combined efforts of host, Tremblaya & Moranella

— Jonathan Eisen · Mon, Jul 08 2013 09:38:04

At #SMBE13 @McCutcheonLab - mealybug has two bacterial symbionts Tremblaya inside bacterial cells & Moranella inside Tremblaya

— Jonathan Eisen · Mon, Jul 08 2013 09:37:04

At #SMBE13 @McCutcheonLab - nutritional endosymbionts of insects have some very weird genomes - small, AT bias, rapid evolution, etc

— Jonathan Eisen · Mon, Jul 08 2013 09:35:41

At #SMBE13 @McCutcheonLab - sap feeding insects make up for amino acids missing from their diet via bacterial symbionts

— Jonathan Eisen · Mon, Jul 08 2013 09:34:07

At #SMBE13 @McCutcheonLab discussing the challenges faced by sap feeding insects on acquiring all the nutrients they need

— Jonathan Eisen · Mon, Jul 08 2013 09:33:35

At #SMBE13 @McCutcheonLab says "this is the best picture of a mealybug you will ever see" & shows pic by @Myrmecos & credits him

— Jonathan Eisen · Mon, Jul 08 2013 09:33:03